The discs are hypoallergenic so the material isn't what is causing a reaction. While uncommon, the reason that some people get a red circle after wearing the disc is that their bodies are likely very drained and depleted of the vital information needed to get into the parasympathetic dominant state. The body literally pulls these EMFs and this vital information from the discs to stimulate the parasympathetic branch and regain autonomic nervous system balance. In short, it is likely that you are maybe experiencing some more stress lately than usual and your body is depending on NuCalm to maintain it. It shouldn't cause you discomfort or irritation, but if it gets like that you can wear it above your left shoulder blade on your back (also an access point to the pericardium) for a little while the skin settles on the wrist.